Abstract

BackgroundCOVID-19 has become the most common cause of acute respiratory distress syndrome (ARDS) worldwide. Features of the pathophysiology and clinical presentation partially distinguish it from ‘classical’ ARDS. A Research and...

Highlights

  • To date, SARS-C­ oV-­2 has infected over 66 million people, causing more than 1.5 million deaths worldwide.[1]

  • Online supplemental table 2 shows the Research and Development (RAND) statements included in the final survey with associated median scores, disagreement index (DI) and final appropriateness outcome category

  • Routine bronchoscopy in intubated patients was rated uncertain, irrespective of the acute respiratory distress syndrome (ARDS) aetiology. This was driven by significant levels of disagreement between panellists denoted by a DI of 1.04 in patients with COVID-­19, despite a median score of 3, whereas in non-C­ OVID-­19 patients, it was due to a median score of 6

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Summary

Introduction

SARS-C­ oV-­2 has infected over 66 million people, causing more than 1.5 million deaths worldwide.[1]. Critical care failure associated with viral pneumonia and sepsis syndrome, leading to acute respiratory distress syndrome (ARDS). COVID-­19 has become the most common cause of acute respiratory distress syndrome (ARDS) worldwide. A Research and Development (RAND) analysis gauged the opinion of an expert panel about the management of ARDS with and without COVID-­19 as the precipitating cause, using recent UK guidelines as a template. The modified online survey comprising 76 questions, subdivided into investigations (16), non-­invasive respiratory support (18), basic intensive care unit management of ARDS (20), management of refractory hypoxaemia (8), pharmacotherapy (7) and anticoagulation (7), was completed again. Conclusion The expert panel found no reason to deviate from the evidence-b­ ased supportive strategies for managing ARDS outlined in recent guidelines

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