Radical mastectomy and conservative surgery for breast cancer patients: comparative analysis of postoperative recurrence, complications, quality of life and cosmetic results

Abstract

Objective Comparing the difference in postoperative recurrence, complications, quality of life and cosmetic results between patients receiving radical mastectomy and breast conserving surgery, provides an evidence of breast conserving surgery superior to radical mastectomy. Methods A retrospective analysis of 477 breast cancer patients cases in Department of General Surgery, Third People′s Hospital of Baoji City from January 2009 to January 2012. These patients were divided into two groups: the control group 229 cases (48%) underwent conservative surgery treatment and the observation group 248 patients (52%) underwent radical surgery. Using SPSS15.0 statistical software analysis and compare with recurrence, postoperative complications, breast cosmetic effect and quality of life for these two groups of patients. Results In breast-conserving group compared with radical mastectomy group, the one and two year recurrence or metastasis rate were not statistically different between the two groups (P>0.05), the incidence of postoperative complications was significantly decreased (P 0.05) and progression free survival (χ2＝4.243, P>0.05) as two indicator of long-term efficacy. Conclusions Conservative surgery compared with radical mastectomyhave less clinical complications, more breast cosmetic effect, better survival quality, and both of them share the same recurrence or metastasis and survival rate, so conservative surgery should be preferable in the clinical application. Key words: Breast neoplasms; Cosmetic techniques; Comparative effectiveness research; Surgical procedures, operative