Abstract

Chromosomal aberration yields were obtained from short term lymphocyte cultures made at various times after an accidental partial body exposure to 192 Ir gamma rays. A rapid decline in the frequency of chromosomal aberrations (CA) has been observed during the first year of follow-up. Dicentric frequencies reduced to one-half, one-third and one-fourth of the original values at 160 days, 240 days and 1 year post-irradiation respectively. The decay of dicentric frequency occurred with a half-life of approximately 168 ± 32 days. A non-Poisson distribution of dicentrics and the presence of a few multi-aberrant cells were consistent with the non-uniform localised exposure

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