Abstract
Induced swelling of isolated residual rat and mouse liver mitochondria following partial removal has been shown to be diminished. This observation can be explained by two possible mechanisms; (a) the conformation of organelles in residual liver is altered and already swollen prior to isolation or, (b) the isolated mitochondria are rendered unreactive to certain swelling inducing systems because of specific changes that have occurred in the membrane.In order to evaluate the former of these proposed mechanisms, quantitative morphometric analysis of the heterogeneity of mitochondria has been attempted in situ by ultrastructural techniques after the manner of Bahr.
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More From: Proceedings, annual meeting, Electron Microscopy Society of America
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