Abstract
Variations in the bone remodeling capabilities of alloxan diabetic and nondiabetic albino rats were assessed by use of a triple fluorochrome labeling technique. Statistical analysis revealed that alloxan diabetes significantly impaired the turnover and remodeling rates of endosteal and periosteal bone (< 0.01). Fluorochrome labeling exhibited distinct differences in the distribution and thickness of new bone apposition and osteon formation between the groups. The head of the condyle labeled more intensely than did the other areas and demonstrated a higher percentage of labeled bone, attesting to the rapidity of bone remodeling. Individual fluorochromes labeled, in a predictable fashion, the events which occurred during a specific time interval.
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