Abstract
Quantitative determinations of acrosin activity in single ejaculates of different human semen quality are presented: freshly collected ejaculates were collected from 256 untreated men. There was a strong correlation (.812) between sperm density and the acrosin activity in samples with 3-250 million spermatozoa/ml. There was no significant difference between normospermia and asthenospermia for mean acrosin content but there was a highly significant (p<.0005) difference between normospermia and oliogospermia with a shift toward higher acrosin activity with decreasing sperm counts. Patient age fructose values pathologic morphology and duration of sexual abstinence showed no correlation with acrosin activity. Determination of the acrosin activity in spermatozoa may be a parameter for the evaluation of the acrosomal membrane system.
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