Abstract
Non-invasive assessment of myocardial function plays a critical role in the management of heart disease. Conventional imaging modalities, such as echocardiography and cine MRI, are widely used for quantitative assessment of global cardiac function and qualitative assessment of regional cardiac function. Quantitative assessment of regional wall motion may additionally improve the accuracy of detecting wall motion abnormalities due to heart disease. Recently, fast cine displacement-encoded (DENSE) MRI was developed to produce relatively high quality strain maps within clinically acceptable breath-hold duration of 12 cardiac cycles [1]. While this pulse sequence is promising for clinical applications, it has not been validated. Therefore, the purpose of this study was to validate the relative accuracy of fast cine DENSE MRI in controls and patients with heart disease.
Highlights
Prophylactic implantation of a cardioverter/ defibrillator (ICD) has been shown to reduce mortality in patients with chronic myocardial infarction (CMI) and an increased risk for life threatening ventricular arrhythmia (VA)
The purpose of this study was to demonstrate a novel approach to imaging the vessel wall and vessel wall calcification using susceptibility weighted imaging [2] (SWI) with no need to suppress the signal from the blood
Optimizing the imaging parameters: The SWI sequence parameters were optimized to allow for the best visualization of the femoral artery lumen in the magnitude images and the arterial wall in the phase images
Summary
Prophylactic implantation of a cardioverter/ defibrillator (ICD) has been shown to reduce mortality in patients with chronic myocardial infarction (CMI) and an increased risk for life threatening ventricular arrhythmia (VA). Methods: In 11 patients (age 0.7 – 27 years) with complex congenital heart disease, surgical questions were directed towards palliative or corrective surgery but consensus about the optimum treatment strategy was not reached using standard diagnostic tools including echocardiography, catheterization and conventional magnetic resonance imaging (MRI). In these patients, three-dimensional printed cast and virtual computer models of the heart were made on the basis of high-resolution whole-heart and/or cineMRI.
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