Abstract
Quantitative assessment of diffuse myocardial fibrosis and edema in patients with and without cardiac involvement of sarcoidosis by cardiovascular magnetic resonance T1- and T2-mapping at 1.5T
Highlights
Cardiac involvement of sarcoidosis hallmarked by inflammatory myocardial processes and subsequent fibrotic myocardial alterations is a life threatening condition that makes early diagnosis favorable
According to CMR results patients were divided into 4 different groups: group 1 (n = 10): patients with positive findings in both exams, group 2 (n = 6): patients with positive findings only in the initial exam; group 3 (n = 8): patients with sarcoidosis but inconspicuous initial CMR exam and group 4 (n = 20): a control group of healthy age matched volunteers with no medical history of sarcoidosis or cardiac disease
T1 relaxation times were significantly longer in patients with positive CMR findings in both the initial examination and the follow-up scan in comparison to all other groups (p < 0,05)
Summary
Our aim was to examine the value of both methods for the differentiation between healthy and diseased myocardium
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