Abstract

We have provided quantitative data on the amount of glucose utilized by the hexosemonophosphate shunt, Embden-Meyerhof and tricarboxylic acid pathways in corneal, lenticular and retinal tissues from trout eyes. In general, the amount of glucose utilized by rainbow trout ocular tissues was lower on a per gram dry weight basis than values for comparable tissues from lake trout eyes. Tissues from discased lake trout eyes had rates of giucose utilization above those for normal controls. With the development of corneal opacities, cataracts, and retinal and pseudobranch degeneration there were concurrent changes in the pattern of glucose utilization by these tissues. Causes for these physiological and biochemical changes as well as the significance of these changes are discussed.

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