Abstract
Platelet-rich plasma (PRP), a proven source of growth factors to enhance bone regeneration, 1 Marx RE Carlson ER Eichstaedt RM et al. Platelet rich plasma: Growth factor enhancement for bone grafts. Oral Surg. 1998; 85: 638 Abstract Full Text PDF Scopus (2019) Google Scholar has recently caught the interest of oral and maxillofacial surgeons as well as several other specialties that deal with bone healing, such as orthopedics, otorhinolaryngology, plastic surgery, neurosurgery, and periodontology. At this time, at least 3 dedicated devices use the general approach of centrifuge technology instead of an autotransfusion machine to produce PRP. Each can make PRP available in the office setting. These are the Smart PReP (Harvest Technologies, Norwell, MA), the Plasma Seal (Plasma Seal, San Francisco, CA), and the Platelet Concentrator (Implant Innovations, Inc. 3i, West Palm Beach, FL). All 3 devices can process PRP with as little as 45 to 60 mL of whole blood and yield 5 to 6 mL of PRP per cycle. Smart PReP is currently the only Food and Drug Administration-approved device for the production of PRP, although the 2 other devices are likely to be approved soon.
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