Abstract
Time dependent fluorescence is observed when single or double stranded DNA with apurinic sites are mixed with 9-NH 2-ellipticine. A concentration dependent plateau is obtained which is linearly related to the ratio of apurinic sites in DNA. We therefore suggest that it is possible to have a direct measurement of apurinic sites in DNA by fluorescence.
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More From: Biochemical and Biophysical Research Communications
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