Quality of Life of Parents and Patients with Biliary Atresia in Native Liver

Abstract

Children with chronic conditions such as biliary atresia may experience several issues that affect their quality of life (QoL). Childhood chronic disease impacts family members and leads to family health impairment. Objective: This study aims to asses the QoL of parents and patients with biliary atresia. Methods and material: The assessment of parent and patient quality of life with biliary atresia was conducted using the Pediatric Quality of Life (PedsQL) parent report and the World Health Organization Quality of Life (WHOQoL).Multivariate linear regression was used for associated factors. This case-control study involved 38 children (0-24 months) with biliary atresia at the Dr. Soetomo General Academic Hospital Surabaya, which was conducted from June to July 2023. Data obtained showed that male and female prevalence was equal (50%). Age <6 months, mothers with high school education, family income >3 million rupiahs, normal nutritional status were frequently in patients with biliary atresia. Based on the WHOQoL questionnaire, the environment was the only domain that impacted the quality of life of the parents significantly (P= 0.005). However, no significant association with patients' QoL was found for the five domains of the PedsQL. The environment factor had a significant impact on the QoL of the patient's parents according to the results of the WHOQoL questionnaire (P= 0.005).