Abstract

BackgroundAsthma is the most commonly occurring respiratory illness during pregnancy. Associations with complications of pregnancy and adverse perinatal outcome have been established. However, little is known about quality of life (QoL) in pregnant women with asthma and how it relates to asthma control particularly for Iran.ObjectiveTo determine the relationship between asthma related QoL and asthma control and severity.MethodsWe conducted a prospective study in pregnant women with asthma. We used the Asthma Control Questionnaire and the Asthma Quality of Life Questionnaire (AQLQ) and the guidelines of the Global Initiative for Asthma for assessment of asthma severity.ResultsAmong 1603 pregnant women, 34 were diagnosed with asthma. Of these 13 had intermittent, 10 mild, 8 moderate and 3 severe persistent asthma. There was a significant decrease of QoL with poorer asthma control (p = 0.014). This decline could be due to limitations of activity in those with poorer asthma control, which is underlined by the significant decline of QoL with increasing asthma severity (p = 0.024).ConclusionAlthough the majority of pregnant women with asthma had a favorable score in AQLQ, reduced QoL was related to increased asthma severity and poor asthma control. This underlines the importance of controlling asthma during pregnancy not only for the prevention of adverse pregnancy outcomes but also for the preservation of QoL.

Highlights

  • Asthma is a chronic inflammatory disease of the airways

  • This decline could be due to limitations of activity in those with poorer asthma control, which is under‐ lined by the significant decline of quality of life (QoL) with increasing asthma severity (p = 0.024)

  • Conclusion: the majority of pregnant women with asthma had a favorable score in Asthma Quality of Life Questionnaire (AQLQ), reduced QoL was related to increased asthma severity and poor asthma control

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Summary

Introduction

Asthma is a chronic inflammatory disease of the airways. This inflammation leads to recurrent episodes of coughing, chest tightness, wheezing, and /or shortness of breath that can affect the patient’s performance and quality of life [1]. Between 8 and 13% of pregnant women have asthma [3, 4]. Asthma may affect quality of life especially in pregnancy; it has an impact on family life, social activities and limits the patients’ physical activity thereby adversely affecting women’s daily life during pregnancy [1]. Asthma is the most commonly occurring respiratory illness during pregnancy. Little is known about quality of life (QoL) in pregnant women with asthma and how it relates to asthma control for Iran

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