Quality of Life among Patients with Neuropathic Pain Attending Outpatient Department of a Tertiary Care Hospital, Kolkata, India

Introduction: Chronic Kidney Disease (CKD) affects 500 million people worldwide. In the US there are 1400 per million of estimated prevalence or established renal failure while in the UK it is recorded more than 600 per million in 2007. This study aims to assess the knowledge on self care measured by structured knowledge questionnaire, and quality of life measured by modified WHO QOL-BREF Scale and try to find out the co-relation between knowledge scores of self care measures and quality of life among chronic renal failure patients undergoing haemodialysis. Methods: A non experimental descriptive correlational design with a quantitative, co-relational survey approach was used for the study. Non probability, purposive sampling was used to select 100 CRF patients undergoing haemodialysis. The conceptual framework was based on Orem?s Self Care Model. The instruments used for data collection were a structured knowledge questionnaire and modified WHO QOL-BREF Scale. The structured knowledge questionnaire was divided into two sections, section I Consists selected socio- demographic perfoma and section II consist Part A- Structured knowledge questionnaire, Part B- Modified WHO QOL-BREF Scale. The main study was conducted among 100 CRF patients undergoing haemodialysis in the month of April and analysis was done by using descriptive and inferential statistics. Karl Pearson?s coefficient of correlation was used to compute the co-relation between knowledge & Quality Of Life. Results: Among the selected 100 patients, Karl Pearson?s coefficient of correlation was found to be rxy = 0.71 since 0< rxy<1, there is positive correlation between the knowledge of self-care measures and Quality Of Life. Conclusion: The study finding revealed that there is positive correlation between the knowledge and quality of life. As the level of knowledge increases, quality of life improves simultaneously.

&#x0D; Introduction: Chronic Kidney Disease (CKD) affects 500 million people worldwide. In the US there are 1400 per million of estimated prevalence or established renal failure while in the UK it is recorded more than 600 per million in 2007. This study aims to assess the knowledge on self care measured by structured knowledge questionnaire, assess the quality of life measured by WHO QOL-BREF Scale and try to find out the relationship between knowledge of self care measures and quality of life among chronic renal failure patients undergoing haemodialysis.&#x0D; &#x0D; Methods: A non experimental descriptive correlational design with a descriptive approach was used for the study. Non probability, purposive sampling was used to select 95 CRF patients undergoing haemodialysis. The conceptual framework was based on Orem’s Self Care Model. The instruments used for data collection were a structured knowledge questionnaire and WHO QOL-BREF Scale. The structured knowledge questionnaire was divided into two sections, socio-demographic variables and knowledge regarding self care measures. The tool was divided into six areas of knowledge such as introduction, clinical features, diagnosis, evaluation, treatment, self care measures and complications of CRF. The main study was conducted among 95 CRF patients undergoing haemodialysis in the month of February to March and analysis was done by using descriptive and inferential statistics. Karl Pearson’s coefficient of correlation was used to compute the co-relation between knowledge &amp; Quality Of Life.&#x0D; &#x0D; Results: Among the selected 95 patients, Karl Pearson’s coefficient of correlation was found to be rxy = 0.86 since 0&lt; rxy&lt;1, there is positive correlation between the knowledge of self-care measures and Quality Of Life.&#x0D; &#x0D; Conclusion: The study finding revealed that there is positive correlation between the knowledge and quality of life. As the level of knowledge increases, quality of life improves simultaneously.

Health-related quality of life of multidrug-resistant tuberculosis patients: A study of eastern Uttar Pradesh, India

Introduction: Psychodermatological conditions, involving psychiatric disorders like depression and anxiety with skin conditions, are often overlooked by healthcare professionals in India. Psychotropic drugs are vital in treatment, but limited studies assess their use and impact on quality of life. This study evaluates psychotropic drug usage, psychological distress, and quality of life in these patients. Methodology: An observational, cross-sectional study was conducted in the psychiatry outpatient department of a tertiary care hospital over one year. Patients of all ages and sexes, diagnosed with psychodermatological disorders and on psychotropic drugs, were included. Sociodemographic and medication data were collected from records. Patients reported dermatological reactions due to psychotropic drugs. Quality of life was assessed using the WHO QoL-BREF scale, and psychological distress with the Kessler’s distress scale. Results: Thirty patients were included. Aripiprazole (50%) and escitalopram (43.33%) were the most prescribed for primary and secondary psychiatric disorders, respectively. Clonazepam was the most common benzodiazepine (60%). Severe psychological distress was found in 55.17% of patients. The physical domain of the QoL-BREF scale was most affected in primary psychiatric disorders. Conclusion: Psychotropic drugs were prescribed based on symptoms. Patients experienced significant psychological distress and poor quality of life, with adverse drug reactions contributing to distress. Judicious use of psychotropic drugs is essential.

To evaluate the quality of life (QoL) of patients with Chagas disease (CD) and the association between QoL domains and several clinical, socioeconomic and lifestyle characteristics of this population. Cross-sectional observational study conducted from March 2014 to March 2017 including a total of 361 outpatients followed at Evandro Chagas National Institute of Infectious Disease, Brazil. QoL was assessed using the Portuguese shorter version of the original WHO Quality of Life questionnaire (WHOQOL-BREF). Information about clinical CD presentation, presence of comorbidities, functional class, previous benznidazole treatment, socioeconomic profile and lifestyle was also obtained. Environment and physical domains presented the worst QoL scores, while the social relationship domain presented the highest score. Multivariate regression analysis demonstrated that variables independently associated with QoL were functional class, sex, clinical presentation of CD, sleep duration, schooling, physical activity level, smoking, income per capita and residents by domicile. The low socioeconomic status and the physical limitations imposed by the disease presented an important impact on the QoL reduction among CD patients, especially on environment and physical domains. Strategies to improve QoL among CD patients should be tailored and consider many different variables to maximise improvements not only of patients' physical but also of their mental health.

Quality of shipboard life plays a significant role, as for a seafarer the ship is both his workplace and home for extended periods. Physical, psychological, social and environmental factors have a substantial impact on the seafarers' quality of life and work. The aim of the study was to analyse the domains determining the factors associated with the seafarers' quality of life at Kochi Port, India. This was a cross-sectional study in which 302 Indian seafarers took part in the research and was conducted in January-February, 2020. WHOQOL-BREF scale was used to explore the four domains of quality of life, and the participants had to rate their perceived satisfaction in each of the domains. The trained researcher conducted a face-to-face interview session using a structured questionnaire. Bivariate and multivariate analysis was used to determine associations and predictors for quality of life, respectively. The majority (80%) of the seafarers were married and were from a rural area (74%). The mean score (standard deviation) was highest for the psychological domain 70.9 (10.5), followed by environmental domain 69.9 (13.2), social relations domain 68.5 (16.9) and physical domain 61.2 (12.8), respectively. A significant association was found between age and the psychological domain (p < 0.05). At the same time, the area of residence had a significant association with physical and psychological domains whereas marital status with physical, psychological and environmental domains (p < 0.05). Daily working hours had a significant association with psychological domains and work experience with the physical and psychological domains (p < 0.05). The findings of this study are an indication for the health policy makers to focus on interventions for improving the quality of life among the seafarers and would also help in enhancing healthy work environments for them.

Hypertension, Diabetes mellitus or both and asthma are very common chronic diseases among Indian rural population which needs continuous monitoring and treatment. Knowledge on disease management, lifestyle, and health care facilities are available which will have direct impact on their Quality of Life. Purpose: Purpose of the study was to identify the quality of life of people living with non-communicable diseases. The study will be helpful to provide need based care and to develop strategies to improve quality of life of community. Methods: A descriptive survey to assess the quality of life of people with non-communicable diseases measured by using WHO QOL BREF scale through interview method. Purposive sampling technique was used to select 200 subjects from selected villages of Udupi District. Result: showed that majority of subjects felt their quality of life was good [Median=4, IQR=3-4]. Majority of subjects [median=3, IQR=3-4] were neither satisfied nor dissatisfied towards their health. Compare to other domains psychological domain has Median=20, IQR=19-21 represents low quality of life. Overall quality of life of subjects with median=93 and IQR= 89- 98 represents good quality of life. Analysis based on diseases showed that people with diabetes mellitus had good quality of life as compared with people with other diseases. There was significant association between quality of life of subjects and age, education, occupation and marital status (P&lt;0.05). Conclusion: Study concluded that majority of the subjects were perceived their quality of life was good especially with those who have diagnosed as diabetes mellitus.

Quality of life assessment in women with spontaneous premature insufficiency: A comparative cross-sectional study

Karol Mathews DVM DVSc DACVECC (Canada) Peter W Kronen Dr Vet Med, DVM DECVAA (Switzerland) Duncan Lascelles BSc BVSc PhD DSAS DECVS DACVS MRCVS (USA) Andrea Nolan MVB DVA PhD DECVAA DECVPT MRCVS (UK) Sheilah Robertson BVMS (Hons) PhD DACVAA DECVAA DECAWBM (WSEL) DACAW MRCVS (USA) Paulo VM Steagall MV MS PhD DACVAA (Brazil/Canada) Bonnie Wright DVM DACVAA (USA) Kazuto Yamashita DVM MS PhD DJCVS (Japan)

BackgroundMedical training is globally recognized as a period marked by significant psychological and lifestyle challenges that may adversely impact students' quality of life (QoL). This issue is particularly critical in low-resource settings, such as Angola, where contextual stressors may further exacerbate these challenges and where no data on the QoL of medical students were previously available.AimTo assess the QoL and its determinants among medical students at Agostinho Neto University in Luanda, Angola.MethodsA cross-sectional study was conducted using a convenience sample of 289 undergraduate medical students at the Faculty of Medicine of Agostinho Neto University (FMUAN) in Luanda, Angola. A cross-culturally adapted version of the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire was used to assess QoL across four domains: physical, psychological, social relationships, and environment. Data were collected through self-completion of the questionnaire at the university facilities. Statistical analyses included descriptive statistics, t-test, ANOVA, chi-square tests, Pearson correlation, and multivariate regression, the latter of which was applied to identify factors associated with QoL domains.ResultsThe sample consisted of 59.2% females, with a mean age of 26.09±6.99 years. Female students were more prevalent in younger age categories (p=0.001), and most students (84.8%) did not report chronic illnesses. The WHOQOL-BREF instrument demonstrated very good internal consistency (Cronbach’s alpha=0.840). Overall, QoL domain scores were low, with the environmental domain showing the lowest mean (45.19±15.70), followed by the physical domain (53.85±15.55). Conversely, the psychological domain had the highest mean score (70.30±11.52). Male students scored significantly lower in the social relationships (62.89 vs. 67.86) and environmental (40.81 vs. 47.14) domains, while female students scored lower in the psychological domain (68.40 vs. 71.63). QoL scores varied across academic years, with third-year students consistently reporting higher scores across most domains, whereas second- and sixth-year students reported the lowest scores. The presence of chronic illnesses was associated with lower QoL in the physical (p=0.016), psychological (p=0.015), and environmental (p=0.007) domains. Most students rated their overall QoL as “neither good nor bad” (51.9%), and about half were satisfied with their health (50.5%). Regression analysis showed that being in the third year and having better perceived overall QoL positively predicted QoL in the physical (β=14.54 and β=10.60, respectively), psychological (β=5.26 and β=5.64, respectively), and social domains (β=6.03 and β=16.27, respectively). Conversely, being a sixth-year student (β=−5.86) and being female (β=−3.72) negatively predicted physical and psychological QoL, respectively.ConclusionsOur findings highlight generally low QoL scores among medical students in Angola, especially in the environmental and physical domains and notably during the initial and final academic years. Being in the third year and having a positive self-assessment of overall QoL emerged as protective factors, while female gender and being a sixth-year student were associated with poorer QoL. These insights underscore the necessity of targeted interventions to address the determinants of QoL and support student well-being in resource-constrained medical education settings such as Angola.

IntroductionCancer can have an impact on Quality of Life (QoL), which can be influenced by an individual’s culture and value system.MethodsWe conducted a cross-sectional descriptive survey involving all women with...

Context: Stressful life events have an impact on common mental disorders. It is also essential to assess the quality of life and pathway of care to mental health to provide a comprehensive picture of these disorders and plan community mental health services. Aims: This study was done to assess the quality of life and stressful life events among patients diagnosed with common mental disorders. We also assessed the pathways to mental health care. Settings and Design: A2 stage cross-sectional study was conducted- first stage of screening followed by 2nd stage of detailed assessment among diagnosed patients in a rural community in Karnataka, South India Method and Material: Patients diagnosed with CMDs were assessed using WHO QOL BREF scale, Presumptive Stressful Life events scale and Pathway to care study pack. Statistical Analysis Used: Descriptive data was analyzed as proportion and pathway to care is presented as diagrammatic representation. Anovaand correlation coefficients were used to assess determinants of quality of life and the role of life events respectively. Results: Financial loss or problems were the most common life events. Mean social relationship domain score was significantly lower and stressful life events in the past 1 year was significantly higher in females. Overall QOL, work capacity, social relationship and environmental domain scores were significantly higher among those who had sought some form of care. Stressful life events experienced ever in lifetime was positively correlated with HAM D score and significant somatic symptoms. Delay after seeking care from general practitioner was much lower compared to other systems of care. Conclusions: QOL and stressful life events were significantly associated with gender. Care seeking in the past had led to improvement of quality of life among the patients.

SP66 Chemotherapy induced neuropathic pain. Clinical diagnosis and treatment

Background:Early psychiatrists inferred that obsessive-compulsive symptoms (OCS) represent a defense against psychosis and prevent the progression of schizophrenia. However, recent clinical research has yielded inconsistent results across studies regarding the link between OCS and the symptom domains of schizophrenia and the influence OCS have on a patient’s functioning and quality of life (QOL).This study aimed to determine whether OCS has any association with the symptom severity, functioning, and QOL of schizophrenia patients.Methods:This cross-sectional study done in a tertiary care hospital consecutively recruited 85 outpatients of schizophrenia in clinical remission over one year. Positive and Negative Syndrome Scale (PANSS), Yale-Brown Obsessive Compulsive Scale (Y-BOCS), WHO Quality of Life Brief Version (WHO QOL-BREF), and Global Assessment of Functioning (GAF) scales were applied.Results:Eighteen patients (21.2%) had OCS (Y-BOCS score of ≥8). Patients with OCS had higher PANSS scores (mean±SD of total score 77.16± 16.4, P < 0.001), suggestive of more severe psychosis, poor functioning overall (mean GAF score 37.35 ± 15.62, P < 0.001), and poor QOL in the psychological domain (P < 0.001). In addition, significant associations were present between the Y-BOCS score and the PANSS (r = 0.65), GAF (r = –0.61), and WHO QOL BREF scores in the physical (r = –0.39), and psychological domains (r = –0.41) (P < 0.001 on all of the above).Conclusions:Patients with OCS have more severe symptoms and a lower QOL. A significant association exists between the intensity of OCS and schizophrenia symptoms, global functioning, and QOL.

Health-Related Quality of Life (HRQL) in Adult Long-Term Hematopoietic Cell Transplant (HCT) Survivors: A Report from the Bone Marrow Transplant Survivor Study.