Abstract
Bilateral pneumothorax is very rare in childhood. Moreover, if it is due to pulmonary involvement of Langerhans cell histiocytosis, it is even rarer in childhood. In our case, a nonsmoker 12-year-old boy presented with bilateral pneumothorax, whose high-resolution computed tomography scan was highly suggestive of pulmonary Langerhans cell histiocytosis. Excision biopsy of a clinically palpable cervical lymph node and histopathological examination and immunohistochemistry positivity for CD1a indicated a diagnosis of Langerhans cell histiocytosis. Clinicians should consider pulmonary Langerhans cell histiocytosis in differential diagnoses in dealing such a case.
Highlights
38 Case reportPulmonary Langerhans cell histiocytosis causing spontaneous bilateral pneumothorax in a child
Bilateral spontaneous pneumothoraces may occur in children as a result of rupture of subpleural blebs into the pleural space, in children with underlying lung diseases such as cystic fibrosis, pulmonary Langerhans cell histiocytosis (PLCH) and those with connective tissue disorders such as Marfan syndromes, cutis lexa, Ehler–Danlos syndrome, and as a result of underlying genetic disorder [1,2]
We report a case of a 12-yearold child presented with bilateral pneumothorax along with a few extrapulmonary features, and PLCH was found to be the cause of his pneumothorax
Summary
Pulmonary Langerhans cell histiocytosis causing spontaneous bilateral pneumothorax in a child. Bhattacharyaya, Arnab Majia, Abhijit Mandalb aDepartment of Pulmonary Medicine, NRS Medical College and Hospital, Kolkata, bDepartment of Pulmonary Medicine, Bankura Sammilani Medical College, Bankura, West Bengal, India. Bilateral pneumothorax is very rare in childhood. If it is due to pulmonary involvement of Langerhans cell histiocytosis, it is even rarer in childhood. A nonsmoker 12-year-old boy presented with bilateral pneumothorax, whose high-resolution computed tomography scan was highly suggestive of pulmonary Langerhans cell histiocytosis. Excision biopsy of a clinically palpable cervical lymph node and histopathological examination and immunohistochemistry positivity for CD1a indicated a diagnosis of Langerhans cell histiocytosis. Clinicians should consider pulmonary Langerhans cell histiocytosis in differential diagnoses in dealing such a case
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
