Abstract
Background: COVID-19 as a pandemic can cause a set of feelings of anxiety, fear and tension in society. In fact, the negative impact of pandemic is not limited to physical health problems and can have serious consequences such as anxiety, depression and stress in people, especially those with neurological diseases. Objectives: The present study was conducted to investigate depression, anxiety and stress in patients with multiple sclerosis and epilepsy during the COVID-19 pandemic. Materials & Methods: In this study, the keywords Depression, Anxiety, Stress, Multiple Sclerosis, Epilepsy and COVID-19 in the title and abstract of articles published in 2020 (May) and 2021 (July) in reputable international scientific databases Searched for Google Scholar, PubMed, Scopus, EMBASE and PsycINFO. The PRISMA checklist was used to review and control the quality of articles. Results: In the search, 394 English articles were retrieved and finally 27 final articles were selected for comprehensive review and data extraction. The results showed that patients with multiple sclerosis and epilepsy experienced depression, anxiety, stress, fear, poor sleep quality, mental fatigue and poor quality of life during the COVID-19 pandemic. Quarantine has limited patients' access to medication and treatment, resulting in increased seizures and disease severity. Conclusion: The COVID-19 pandemic reduced the mental health of patients with multiple sclerosis and epilepsy. Given that the psychological consequences of the outbreak of COVID-19 are possible to be associated with patients with multiple sclerosis and epilepsy for years, it is necessary to adopt psychological interventions to reduce psychological distress in these patients
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