Abstract

(N Engl J Med. 2018;379:907–909) Ensuring that a pregnant woman has access to potentially life-saving treatments while safeguarding her fetus is a delicate balancing act that requires careful evaluation of risks and benefits to both the mother and fetus. In the present perspective article, Rasmussen and colleagues discuss the recent safety signal released by multiple organizations regarding the use of dolutegravir, an antiretroviral medication, during pregnancy and the potential for neural tube defects.

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