Abstract
In a multicenter comparative trial, 15-methyl prostaglandin F2α (PGF2α), 0.92 mg., was administered by extra-amniotic injection to 660 patients. Abortion of the fetus occurred within 24 hours in 479 patients (72.6 per cent) and within 36 hours in 530 patients (80.3 per cent). Abortion was complete in 31 per cent of the cases. The commonest side effects were vomiting and diarrhea, but these symptoms were not severe, the mean frequencies being 0.9 episodes of vomiting per patient and 0.7 episodes of diarrhea per patient. It is concluded that this method is safe and effective for the induction of abortion.
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