Abstract
BackgroundThe property values of therapeutic gas mixtures are important in designing devices, defining delivery parameters, and in understanding the therapeutic effects. In the medical related literature the vast majority of articles related to gas mixtures report property values only for the pure substances or estimates based on concentration weighted averages. However, if the molecular size or structures of the component gases are very different a more accurate estimate should be considered.FindingsIn this paper estimates based on kinetic theory are provided of density, viscosity, mean free path, thermal conductivity, specific heat at constant pressure, and diffusivity over a range of concentrations of He-O2, Xe-O2, N2O-O2 and N2-O2 mixtures at room (or normal) and body temperature, 20 and 37°C, respectively and at atmospheric pressure.ConclusionsProperty value estimations have been provided for therapeutic gas mixtures and compared to experimental values obtained from the literature where possible.
Highlights
Inhaled therapeutic gases in use today include helium (He) for respiratory treatments, and xenon (Xe) and nitrous oxide (N2O) for anesthesia
Property value estimations have been provided for therapeutic gas mixtures and compared to experimental values obtained from the literature where possible
The property values of therapeutic gas mixtures are important in designing devices, defining delivery parameters, and in understanding the therapeutic effects
Summary
Inhaled therapeutic gases in use today include helium (He) for respiratory treatments, and xenon (Xe) and nitrous oxide (N2O) for anesthesia For clinical applications these gases are used in the form of mixtures with oxygen in a range of concentrations (typically starting from 20% oxygen (O2) concentration by volume, which is equivalent to a mole fraction of 0.20) so as to maintain adequate oxygenation. In the medical literature the vast majority of articles related to gas mixtures report property values only for the pure substances or estimates based on (volume or molar) concentration weighted averages [1,2,3,4,5,6,7]. In the medical related literature the vast majority of articles related to gas mixtures report property values only for the pure substances or estimates based on concentration weighted averages. If the molecular size or structures of the component gases are very different a more accurate estimate should be considered
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