Abstract
The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collaterals; and do primary afferent inputs to the various regions of nV arise from individual cells? Pairs of injections, using contrasting dyes, were made into the following target area combinations: ventrobasal thalamus-ipsilateral superior colliculus, cerebellum-contralateral thalamus, nucleus principalis of nV-contralateral thalamus, and nucleus principalis of nV-subnucleus caudalis of spinal nV. In general, numerous neurons throughout all subdivisions of nV and within the trigeminal ganglion were labeled by a single dye following the injections. In addition, many cells in a similar distribution were found to be doubly-labeled following such injection combination. These data demonstrate the existence of significant subpopulations of first- and second-order neurons that project to multiple targets via divergent axonal ramifications throughout the rat sensory trigeminal system.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.