Abstract
Summary Progressive multifocal leukoencephalopathy without immunosuppression – a rare case We report the case of a 73-year-old male patient presenting a colourful neurological picture. After progressive multifocal leukoencephalopathy (PML) had been diagnosed the neurological deficits were rapidly progressive and the patient died within a few days. He was not immunodeficient. PML is more often encountered in patients with immunodeficiencies, e.g. advanced HIV infection, where dormant JC virus may reactivate. Our patient was formerly diagnosed with chronic cold agglutinin disease with only minor haemolysis. No association of this entity with PML could be found.
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