Abstract

The mechanism of coronary artery thrombosis(CAT)caused by Kawasaki disease is not clear yet.Endothelial injury, hypercoagulability and hemodynamic change of coronary arteries are now considered as the main causes in recent studies.As The clinical symptom of acute thrombus caused by Kawasaki disease is unconspicuous, cardiac ultrasound should be use actively and thrombolytic therapy should be performed within 12 hours after thrombus formation or the onset of acute myocardial infarction.Intervention or intravenous thrombolysis are both proved to be effective.Treatment with oral antitplatelet drugs, such as aspirin, combine with warfarin is suggested to relieve acute myocardial infarction in the chronic phase.The adverse reactions of antithrombotic and anticoagulant drugs should be monitored though they are minor. Key words: Kawasaki disease; Thrombosis; Endothelial cell; Treatment

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