Abstract

Microtus fortis is a valuable resource of wild animals in China.To develop an experimental model of Microtus fortis has been listed as a research project in national program and under extensive study.Up to date,schistosomiasis japonicum is an important zoonosis,which remain8 an important public health issue in China.Microtus fortis is a unique wild mammalian resistant to schistosomiasis 80 far.At present,more intensive studies are needed in its taxonomy,anatomy,purification,embryo cryopreservation and transplantation,especiany in molecular genetics to develop a useful experimental model for researches on the resistant mechanism to S.japonicum infection and transgenic breeding of schistosomiasis-resistant animal in laboratory.In this paper.the progress in establishment of Microtus fortis experimental model and its application in the research of schistosomiasis japonica were reviewed. Key words: Microtus fortis; Anti-schistosomiasis; Experimental animal model

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