Prognostic usefulness of changes in hemostatic parameters of dogs with parvoviral enteritis

Abstract

The aim of the work was to study the prognostic usefulness of changes in hemostatic parameters of dogs with parvoviral enteritis.Compared the results of a study of the blood of the dead (n = 4) and the surviving dogs (n = 11) on days 3 and 5 of illness between 2 and 6 months of age among themselves and with the results of blood tests of healthy dogs in the control group (n = 10).On the 3rd day of the disease, we can identify as markers of an unfavorable prognosis a decrease in platelet count to 285,97±14,84х109/L, an increase inMPV to 8,5±1,7 fl and PCT to 0,53±0,02%, an increase in SIAP with ADP to 131,67±9,28% and ristomycin to 127,77±14,71%, a decrease in disaggregation with ADP to1,03±1,03% and ristomycin to 0,08±0,08%, an increase in the amount of fibrinogen to 5,2±0,49 g/l and SFMC to 12,97±1,15 mg/100ml along with a decrease in the activity of antithrombin to 105,3±3,16%.On the 5th day of illness, such parameters as a progressive decrease in platelet count to227±15,64 х109/L are associated with a decrease in the MPV to 5,5±1,2 fl and PCT to 0,21±0,03%, a decrease in SIAP with ADP to 31,67±12,03%, collagen to 15,53±4,26% and ristomycin to14,8±5,6%, reduction of disaggregation with all inductors, lengthening of PT from14,17±0,24 to18,5±2,9 sec., TT from9,07±0,58 to 26,37±1,57 sec. and APTT from18,03±1,54 to 26,37±1,57 sec., increase in SFMC to17,3±1,17mg/100ml, a decrease in fibrinogen to 2,73±0,89g/l and antithrombin activity to 88,63±14,93%.