Abstract
Recently, a conformational variant of p53 (U-p53AZ ) has been identified as a lead biomarker for Alzheimer’s Disease (AD). A highly sensitive, specific and reliable IP-SACI-MS (described as AlzoSure® Predict) was used to detect U-p53AZ in plasma samples from AD-individuals at different stages of the disease to validate its AD-dementia prognostic value.
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