Abstract
To improve the microbial production of vitamin B12, we applied a hollow-fiber module to cultivation of the vitamin producers. By the removal of growth inhibitors, very high concentrations of cells and vitamin B12 were obtained comparing to the batch culture. We obtained 227 g dry cells/l and 52 mg vitamin B12/l with Propionibacterium shermanii and 33.4 g dry cell/l and 92.5 mg vitamin B12/l with Butyribacterium methylotrophicum by this cultivation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
