Abstract

The direct production of 99mTc through (p, 2n) reaction on natural molybdenum target and enriched 100Mo target was investigated. Separation of technetium radionuclide from the irradiated 100Mo target by a new method using Dowex-1 ion exchange resin as well as by the standard solvent extraction (methyl ethyl ketone) method was studied. An automated computer controlled module was developed based on the Dowex-1 separation methodology. The new chemical separation method recovered more than 80 % of 99mTc from the irradiated target. The recovered pertechnetate had requisite radionuclidic, radiochemical and chemical purity for the preparation of 99mTc-radiopharmaceuticals.

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