Abstract

The value of a pharmaceutical company may be defined as its pipeline or portfolio of products and their potential value in the marketplace. One strategy to help mitigate the multitude of risks in pharmaceutical product development is to balance a portfolio across therapeutic areas, levels of risk and potential for returns. Risks include unexpected toxicities, therapeutic failure and inappropriate risk-benefit for the patient, as well as technical, financial, regulatory, political or social failure. Strategic reviews of a company’s portfolio will help ensure its product line-up is balanced appropriately to meet corporate goals and that product risks have been considered.

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