Problems of Formal Genesis of Carcinoma of the Stomach

Abstract

For early diagnosis, classification and prognosis of stomach carcinomas, the problems concerning their formal genesis are of the same importance as those of frequency, different in each country of the world. We know from numerous studies (SEGI and KURIHARA, 1966; DOLL et al. 1966, and others) that the highest mortality rates for stomach carcinoma occur in Japan, Chile, Iceland and some East-European countries. Germany still has a relatively high mortality rate, whereas in the USA, Canada, Australia and other countries the risk of stomach carcinoma is relatively low. Such big difference in frequency usually concerns a younger age-group; stomach carcinoma is differing substantially less in its incidence among the respective older age-groups. This fact has some relevance also for the problems of formal genesis: LAUREN (1965), TAUCHI et al. (1960) and others have shown that, despite all heterogeneity, different types of stomach carcinoma (oviously developing differently also in terms of form) have differing age distributions. In fact, MUNOZ et al. (1968) were able to show that there are really differences in frequency of carcinoma types, and that they depend on the different total frequency.