Abstract

Today, Convolutional Neural Networks (CNNs) are the leading method for image denoising. They are traditionally trained on pairs of images, which are often hard to obtain for practical applications. This motivates self-supervised training methods such as Noise2Void~(N2V) that operate on single noisy images. Self-supervised methods are, unfortunately, not competitive with models trained on image pairs. Here, we present 'Probabilistic Noise2Void' (PN2V), a method to train CNNs to predict per-pixel intensity distributions. Combining these with a suitable description of the noise, we obtain a complete probabilistic model for the noisy observations and true signal in every pixel. We evaluate PN2V on publicly available microscopy datasets, under a broad range of noise regimes, and achieve competitive results with respect to supervised state-of-the-art methods.

Highlights

  • Image restoration is the problem of reconstructing an image from a corrupted version of itself

  • In this work we show that MMSEPN2V consistently outperforms other self-supervised methods, and in many cases, leads to results that are competitive even with supervised state-of-the-art content-aware image restoration (CARE) networks

  • We have introduced Probabilistic Noise2Void (PN2V), a fully probabilistic approach extending self-supervised CARE training

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Summary

Introduction

Image restoration is the problem of reconstructing an image from a corrupted version of itself. Self-supervised training methods, such as Noise2Void (N2V) (Krull et al, 2019), are a promising alternative, as they operate exclusively on single noisy images (Batson and Royer, 2019; Krull et al, 2019; Laine et al, 2019). This is enabled by excluding/masking the center (blind-spot) of the network’s receptive fields. It does not depend on the content of the images that are to be denoised

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