Abstract
A 78-year-old Caucasian man with history of long-standing HIV well managed on long term antiretroviral therapy, presented to the emergency department with dry cough and shortness of breath of three weeks duration. He had a massive left sided pleural effusion requiring drainage. Flow cytometry analysis of the fluid demonstrated very dim CD45, positive for CD38 and CD138, and aberrant T lineage markers. The cytology was highly cellular with a lymphocyte population staining for plasma cells markers, HHV8 and aberrant T lineage markers.
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