Abstract

Objective To investigate the etigology, pathogenesis, clinical features, diagnosis, treatment and prognosis of primary bronchial and pulmonary amyloidosis. Methods We retrospectively studied 56 primary bronchial and pulmonary amyloidosis cases reported in Chinese literature during 2000-2017 and one in our hospital. Results ①The main clinical manifestations included cough, sputum, short breath and hemoptysis.②Thickening of lung markings was the most common chest X-ray; Airway wall thickening and stenosis was the most common CT manifestation and endoscopic finding.③Pulmonary function test was mainly obstructive ventilation function.④A mean eosinphilic deposit in bronchus and lung after Haematokylin and Eosin (HE) staining of the lesion, the Congo red staining positive.⑤The treatments of the disease included intervention, chemotherapy, surgery and so on. Conclusions Primary bronchial and pulmonary amyloidosis is rare, correct diagnose needs pathological examination and there is no specific treatment for it currently. Key words: Amyloidosis; Bronchi; diagnosis; treatment; prognosis

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