Abstract

Primary B-cell lymphoma of the pelvic bone in a young patient: Imaging features of a rare case

Highlights

  • Primary bone lymphoma is encountered in approximately 3-7% of primary bone tumors

  • We present a rare case of Non-Hodgkin’s lymphoma occurred in a young patient and illustrate the diagnostic difficulty of primary bone lymphoma as well as emphasize the importance of multi-modality correlation for the differential diagnosis of Paget’s disease vs. primary bone lymphoma

  • The patient was found to have stage IVE disease according to the International Extranodal Lymphoma Study Group (IELSG), with extensive bone marrow lesions involving the left hemipelvis [3]

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Summary

Introduction

Primary bone lymphoma is encountered in approximately 3-7% of primary bone tumors. The majority of the cases represent limited disease with an age predilection of 20-50 years [1,2,3]. For the incidental finding of diffusely intense uptake involving the left hemipelvis, Paget’s disease was favored over osteosarcoma and Ewing’s sarcoma. It was not until the MRI study that showed findings inconsistent with Paget’s disease and suspected primary bone lymphoma because of the extensive T1 signal loss due to bone marrow replacement with contrast enhancing soft tissue in the absence of cortical bone destruction, with histopathology revealing extranodal diffuse large B-cell lymphoma.

Results
Conclusion

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