Abstract
Epidemiologic studies and small-scale intervention trials in human beings indicate that fish and fish oils have profound effects on platelets, produce a favorable blood lipid profile, and lower arterial pressure. Data from the Greenland Eskimos, Japan, the Netherlands, and the Western Electric Company suggest that increased consumption of fish may lead to a decrease in mortality from ischemic heart disease. We review the role that fish and fish oils have in preventive cardiology. Although it appears prudent for Americans to eat more fish and less red meat, as recommended by the American Heart Association, further studies of the long-term efficacy and safety of fish oils are needed before recommending their routine use by the general population or by cardiac patients. —“Fish oil is a whale of a story that is getting bigger with each telling!” (Rogans JA, N Engl J Med, 1987.1)
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