Abstract
AbstractRadiation treatment of large uveal melanomas especially when they are infiltrating the ciliary body is often followed by the development of neovascular glaucoma. The reason for this is associated with the development of large hypoxic retinal areas and also necrosis of the irradiated tumor, that has been defined as “toxic tumor syndrome”. Resection of the tumour after successful irradiation is a very helpful way of treating this potential post irradiation complication. Prevention of the development of secondary glaucoma is even better for log‐term preservation of visual function. Especially when the tumor is located anteriorly where tumor endoresection is hazardous due to ciliary body hemorrhage, transscleral resection is a very helpful alternative. On the long term patients that have undergone this combined treatment regiment have a larger probability of eye and visual function preservation.
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