Abstract
Background: Safe blood transfusion is of utmost importance as an unsafe blood transfusion bears lot of burden on human life and economy. Amongst the blood transfusion complications, transmission of certain infections like HIV, Hepatitis B, Hepatitis C and Syphilis are most significant for the long term detrimental side effects. The present study was carried out with an aim to assess the trend and seroprevalence of transfusion transmitted infections (TTIs) among blood donors at our blood bank. Methods: The present retrospective study was carried out at blood bank attached to Pacific Medical College and Hospital, Udaipur, Rajasthan after ethical committee approval. Data regarding sex of the donor, type of donors and screening test results were collected from the records of blood bank over a period of 3 years (May 2014 - June 2016). Result: Total 2015 donors were registered of which 1944 (96.5%) were males and 71 (3.5%) were females. Replacement donors (68.7%) were more compared to voluntary donors (31.3%). Overall prevalence of TTIs in our blood bank is 2.38% of which prevalence of Syphilis (1.2%) was highest followed by HBV (0.89%), HIV (0.14%), and Malaria (0.1%). Conclusion: TTIs were more common in replacement donors than in voluntary donors, hence more voluntary donations need to be encouraged. Extensive donor screening by more sensitive methods to detect infections early can reduce the risk of TTIs. Despite high financial cost, adoption of newer screening methods like NAT can help in reducing the prevalence rate of TTIs to a large extent. DOI: 10.21276/APALM.1095
Highlights
IntroductionProviding safe and adequate blood should be an integral part of every country’s national health care policy and infrastructure.[1] Amongst the blood transfusion complications, transmission of certain infections (TTIs) like Human Immunodeficiency Virus (HIV), Hepatitis B and C and Syphilis are most significant for the long term detrimental side effects
Banking of blood is important as it is one of the most precious commodities
transmitted infections (TTIs) were more common in replacement donors than in voluntary donors, more voluntary donations need to be encouraged
Summary
Providing safe and adequate blood should be an integral part of every country’s national health care policy and infrastructure.[1] Amongst the blood transfusion complications, transmission of certain infections (TTIs) like HIV, Hepatitis B and C and Syphilis are most significant for the long term detrimental side effects. Safe blood transfusion is of utmost importance as an unsafe blood transfusion bears lot of burden on human life and economy. Amongst the blood transfusion complications, transmission of certain infections like HIV, Hepatitis B, Hepatitis C and Syphilis are most significant for the long term detrimental side effects. The present study was carried out with an aim to assess the trend and seroprevalence of transfusion transmitted infections (TTIs) among blood donors at our blood bank
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