Asian Journal of Pharmaceutical and Clinical Research
PREVALENCE OF SERUM SUBOPTIMAL VITAMIN D3 LEVELS AND ITS CORRELATION WITH TREATMENT OUTCOME, SOCIODEMOGRAPHIC PROFILE AMONG CANCER PATIENTS: A RETROSPECTIVE ANALYSIS
Publication Date Aug 7, 2022
Objectives: In areas of etiology and prevention of cancer research, Vitamin D3 is currently one of the most promising agents. By virtue of anti-inflammatory, immunomodulatory, antiangiogenic, and proapoptotic effects, Vitamin D3 may inhibit carcinogenesis, cancer cell proliferation, and tumor progression. We wanted to study the prevalence of Vitamin D3 deficiency among cancer patients and whether there is any correlation between this Vitamin D3 level with response to the treatment of cancer and survival. Methods: Between, January 2014 and December 2017, 199 patients, who completed treatment at our radiotherapy department, were included in this study. In a non-fasting state, a venous blood sample was obtained during the follow-up period, and the serum level of Vitamin D3 was determined by chemiluminescence immunoassay method. Results: A higher prevalence of suboptimal D3 concentration was seen in patients with stable or progressive disease (PD) than in those patients cured, this was statistically significant. The complete response versus partial response and PD p-values are 0.0001 and 0.0008, respectively. Overall survival (OS) difference between D3 sufficiency and insufficiency is not statistically significant (p-0.4422). However, OS difference between D3 sufficiency and deficiency is statistically significant (p-0.0001). Similarly, the OS difference between D3 insufficiency and deficiency is statistically significant (p-0.0001). Conclusions: Vitamin D3 level is significantly associated with response and there is also a posi...
D3 Deficiency Vitamin D3 Level Prevalence Of Vitamin D3 Deficiency Serum Level Of Vitamin D3 Overall Survival Difference Vitamin D3 Areas Of Etiology Chemiluminescence Immunoassay Method Non-fasting State Suboptimal Concentration
AI-powered Research feed
Introducing Weekly Round-ups!Beta
Round-ups are the summaries of handpicked papers around trending topics published every week. These would enable you to scan through a collection of papers and decide if the paper is relevant to you before actually investing time into reading it.
Climate change Research Articles published between Sep 19, 2022 to Sep 25, 2022
Sep 26, 2022
Articles Included: 5
Disaster Prevention and Management ISSN: 0965-3562 Article publication date: 20 September 2022 This paper applies the theory of cascading, interconnec...Read More
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on “as is” basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The Copyright Law.