PREVALENCE OF METABOLIC SYNDROME IN COPD CASES IN CENTRAL INDIA AND ITS CORRELATION WITH BMI

Abstract

BACKGROUND: COPD is the third leading cause of death worldwide with more than 90% of COPD deaths occuring in low and middle income countries. While metabolic syndrome is a cluster of the most dangerous cardiovascular risk factors , dened to be associated with prothrombotic and proinammatory states. About 20%- 25% adult population of the world have Metabolic syndrome and are three times more likely to have coronary artery disease or stroke . Increasing evidence shows association between Metabolic Syndrome in COPD. However, the frequency of Metabolic Syndrome and its individual components are not still been clearly shown especially in Indian population in central India . METHODS: This was a cross sectional study conducted at Department of Respiratory Medicine, Gandhi Medical College & Hamidia hospital, Bhopal. 100 spirometrically conrmed COPD cases were enrolled after permission from institutional ethics committee . Detailed history , clinical examination , laboratory parameters and anthropometric parameters were taken. RESULTS: Mean age of patients with COPD was 60.34±10.39 years .Mean weight, height and BMI of patients was 55.86±9.43 2. 2 kg, 160.47±7.58 m and 21.65±3.01kg/m .Majority - 57% patients had normal BMI (18.5 to 22.9 kg/m ). About 25% and 11% patients were overweight and underweight respectively. Metabolic syndrome was found to be present in 32% of the patients with COPD. BMI of patients with metabolic syndrome was signicantly higher as compared to COPD patients without metabolic syndrome (p<0.01). CONCLUSION: The prevalence of metabolic syndrome in COPD was 32% and BMI in COPD patients with metabolic syndrome was signicantly higher than those without metabolic syndrome .