Abstract
Chronic hepatitis C virus (HCV) infection is associated with a significant 31% higher risk of developing non-dialysis chronic kidney disease (ND-CKD) [1]. Furthermore, in patients with ND-CKD, HCV infection is associated with a faster decline of the estimated glomerular filtration rate (eGFR) over time and a higher risk of end-stage kidney disease compared with HCV-negative patients [2–5]. In the ND-CKD population, estimates of the prevalence of HCV infection are sparse and inconsistent and has been mainly evaluated by testing only anti-HCV antibodies without taking into account the active virus replication, assessed by nucleic acid testing (NAT) [6]. However, the wider use of direct antiviral agents (DAAs) as well as the spontaneous viral clearance make immunoassay testing insufficient for correctly estimating HCV prevalence among ND-CKD patients. Therefore we designed this observational multicentre study in order to estimate the prevalence of HCV in the ND-CKD population...
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Schedule a callMore From: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
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