Abstract
Various haemoglobinopathies are major public health problem in Gujarat, a state located in the western part of India. The data pertaining to their occurrence and prevalence in the state of Gujarat are scarce and hence it was considered worthwhile to study the burden of haemoglobinopathies in Gujarat, India. A retrospective analysis of blood samples of 428 cases referred to the pathology laboratory from various private practitioners/Government hospitals for the workup of anemia or other blood related disorders was done by Bio-Rad D-10 instrument. 153 (35.7%) patients out of 428 had haemoglobinopathies. Thalassaemia minor (70 cases, 16.35 %), thalassaemia major (32 cases, 7.48%), sickle cell disease (22 cases, 5.14 %) and sickle cell trait (12 cases, 2.8%) were most common haemoglobinopathies. Less prevalent haemoglobinopathies were sickle-β-thalassaemia, α,βthalassaemia heterozygote, Hb D trait, Hb E trait, Hb Ethalassaemia, Hb D disease, Hb E disease and sickle D disease. Our study indicates that almost all the common haemoglobinopathies are prevalent in Gujarat but sickle cell trait/anemia and β thalassaemia are very common. Various haemoglobinopathies are major public health problem in Gujarat, a state located in the western part of India. The data pertaining to their occurrence and prevalence in the state of Gujarat are scarce and hence it was considered worthwhile to study the burden of haemoglobinopathies in Gujarat, India. A retrospective analysis of blood samples of 428 cases referred to the pathology laboratory from various private practitioners/Government hospitals for the workup of anemia or other blood related disorders was done by BioRad D-10 instrument. 153 (35.7%) patients out of 428 had haemoglobinopathies. Thalassaemia minor (70 cases, 16.35 %), thalassaemia major (32 cases, 7.48%), sickle cell disease (22 cases, 5.14 %) and sickle cell trait (12 cases, 2.8%) were most common haemoglobinopathies. Less prevalent haemoglobinopathies were sickle-?-thalassaemia, ?,?thalassaemia heterozygote, Hb D trait, Hb E trait, Hb Ethalassaemia, Hb D disease, Hb E disease and sickle D disease. Our study indicates that almost all the common haemoglobinopathies are prevalent in Gujarat but sickle cell trait/anemia and ? thalassaemia are very common.
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