Prevalence, incidence and epidemiology of childhood uveitis.

Abstract

To analyse the prevalence, incidence and aetiology of paediatric uveitis. A retrospective, population-based cohort study of Finnish children with uveitis in Northern Ostrobothnia Hospital District in 2008-2017. The data included parameters for age, gender, age at diagnosis, laterality, chronicity, anatomical distribution of the disease, aetiology and systemic association. One hundred fifty patients aged <16years (mean age 6.9±3.9years) with uveitis were included, out of whom 53% were girls. The first uveitis episode occurred at 1-6years in 59%, and 62% of them were girls. In the age group of 7-15years, boys were diagnosed with uveitis more frequently than girls (61% versus 39%, respectively). Seventy percent of the girls were diagnosed with their first uveitis episode at the age of 1-6years, whereas only 48% of the boys were diagnosed at that age. The prevalence of uveitis increased from 64/100000 children <16years in 2008 (95% CI, 47.7-84.2) to 106/100000 in 2017 (95% CI, 84.6-130.2). The incidence of childhood uveitis in 2008-2017 was 14/100000 person-years in children <16years (95% CI, 11.3-16.5). Eighty-seven percent of the cases were non-infectious, 9% were infectious, and 3% had masquerade syndromes. Sixty-one percent of patients had juvenile idiopathic arthritis (JIA). The prevalence of paediatric uveitis has increased during the last decade in both genders. Uveitis is more frequent in girls, and they were diagnosed at a younger age than boys. Idiopathic cases and JIA accounted for a majority of aetiological features.