Abstract
Introduction Urinary tract infection (UTI) is a frequent condition encountered in clinical settings. Empirical treatment is common. The treatment without urine culture and sensitivity leads to antimicrobial resistance. This is a major global concern.
 Objective The objective of this study was to find the prevalence and susceptibility pattern of Bacterial Uropathogens among patients with Urinary Tract Infection at Birat Medical College and Teaching Hospital of eastern Nepal.
 Methodology A cross-sectional study was conducted among patients with UTI attending Birat Medical College and Teaching Hospital from August 2018 to December 2018. The sample size of the study was 530. Ethical clearance was taken from the Institutional Review Committee of Birat Medical College and Teaching Hospital (Ref: IRC-PA-009/2075-76). Data were entered into Microsoft Excel and analyzed by using SPSS.
 Results The prevalence of bacterial uropathogens among urine culture was 66.04%. The common uropathogens isolated were E.coli (66.9%) and Klebsiella spp (15.1%). E.coli was highly susceptible to Chloramphenicol (100%) followed by Ceftrixone (82.4%), Cefpodoxime (77.8%) and Amikacin (77.9%); while Klebsiella spp were susceptible to nalidixic acid (40%) followed by co-trimoxazole (17.9%).
 Conclusion Almost 2 out of 3 samples had bacterial uropathogens isolated. E. coli and Klebsiella spp were common. Chloramphenicol and Nalidixic acid were highly susceptible to E.coli and Klebsiella spp respectively.
Highlights
Urinary tract infec ons (UTI) describe microbial coloniza on and infec on of structures of the urinary tract
A cross-sec onal study was conducted among pa ents with UTI a ending Birat Medical College and Teaching Hospital from August 2018 to December 2018
E.coli was highly suscep ble to Chloramphenicol (100%) followed by Ce rixone (82.4%), Cefpodoxime (77.8%) and Amikacin (77.9%); while Klebsiella spp were suscep ble to nalidixic acid (40%) followed by co-trimoxazole (17.9%)
Summary
Urinary tract infec ons (UTI) describe microbial coloniza on and infec on of structures of the urinary tract. A study at Kathmandu Medical College Teaching Hospital found that most common pathogens isolated were E.coli (79.1%) followed by Klebsiella spp (11.7%), Citrobacter spp (8.0%) and Proteus spp (7.0%).[8] In another study, the highest percentage of sensi vity was found with Ofloxacin (63.0%), Ciprofloxacin (62.0%), Nitrofurantoin (49.1%) and Amikacin (40.1%).[9] Pa ents a ending Birat Medical College and Teaching Hospital has an unknown prevalence of UTI with unknown drug suscep bility pa ern. Previous studies conducted in surrounding communi es of this medical college teaching hospital reported that selfmedica on was 44.04% with an bio c being the second most common group for UTI.[10] Due to this, it creates a gap in the treatment of UTI.
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