Abstract

To establish the presence of Patent foramen ovale (PFO) & Right to Left shunt in patients with migraine & stroke The presence of a right to left shunt & PFO in patients with migraine can be detected using Transcranial Doppler (TCD) & micro bubbles. 106 patients with a history of migraine & stroke were studied from 2012 February to December 2018.The patients were in the age group 28 to 54 years. All patients were subjected to TCD bubble study with valsalva meneuvre. TCD bubble study was done after fixing a head frame & monitoring the Middle cerebral artery (MCA). 9 ml of saline & 1 ml of air was mixed & agitated and injected into the right ante cubital vein. The procedure was done before & after valsalva maneuvre. The timing of arrival of micro bubbles on TCD after injection was noted. The number of high intensity transient signals (HITS) were quantified. In our study 46% of patients who had PFO. 62% of the PFOs were large causing spencer grade 3 & above shunting at the PFO. 38% of the PFOs were spencer grade 1 & 2. TCD showed evidence of PFO in a high proportion of patients with migraine & stroke. TCD is a very sensitive & reliable method of detecting right to left shunt at PFO level.TCD can help in predicting patients with migraine who are at a high risk of developing stroke

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