Abstract
Juvenile idiopathic arthritis (JIA) is the most common disease associated with uveitis of childhood. The pathogenesis of JIA-associated uveitis (JIAU) is undefined, although there is evidence for a B-cell-mediated autoimmune process with a probably pathogenetic role for autoantibodies.
Highlights
Pediatric Rheumatology European Society (PReS)-FINAL-2150: Antiocular antibodies in children with juvenile idiopathic arthritis-associated uveitis
Juvenile idiopathic arthritis (JIA) is the most common disease associated with uveitis of childhood
The patient groups differed with respect to their presence of antibody-binding to the sections: JIA-associated uveitis (JIAU) (94%), JIA (75%), IAU (75%), and healthy controls (29%) to uveal and/or retinal structures
Summary
Juvenile idiopathic arthritis (JIA) is the most common disease associated with uveitis of childhood. The pathogenesis of JIA-associated uveitis (JIAU) is undefined, there is evidence for a B-cell-mediated autoimmune process with a probably pathogenetic role for autoantibodies
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