Abstract

A multinational collaborative effort aimed to develop a new set of criteria for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (sjia) is ongoing. The data-collection phase of the project has been recently completed

Highlights

  • Pediatric Rheumatology European Society (PReS)-FINAL-2141: Clinical features, therapeutic interventions and outcome of 362 patients with macrophage activation syndrome enrolled in a multinational survey

  • A multinational collaborative effort aimed to develop a new set of criteria for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis is ongoing

  • 362 patients with sjia-associated MAS were entered in the study website by 95 investigators (78.2% paediatric rheumatologists, 21.8% paediatric hemato-oncologists) from 33 countries. 208 patients (57.5%) were females

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Summary

Introduction

PReS-FINAL-2141: Clinical features, therapeutic interventions and outcome of 362 patients with macrophage activation syndrome enrolled in a multinational survey Introduction A multinational collaborative effort aimed to develop a new set of criteria for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (sjia) is ongoing. Objectives To describe the demographic, clinical, laboratory, and histopathologic features, therapeutic interventionsand outcome of 362 children with MAS collected in the study. Methods Patient data were collected retrospectively in a web-based database, developed and handled at the coordinating centre

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