Abstract
Shellac is a natural biodegradable oligoester produced by lac insects, containing reactive functional groups such as hydroxyl, carboxylic acid, ester, aldehyde, and alkene groups, which can be used for chemical functionalization. Herein, shellac is functionalized with poly(ethylene glycol) (PEG) or poly(N-isopropylacrylamide) (PNIPAM) via grafting-to and grafting-from methods. The functional polymer conjugates are then processed as nanoparticles by the miniemulsion-solvent evaporation process. Shellac-PEG nanoparticles are enriched with apolipoprotein AI after incubation in fetal bovine serum at 37 °C. Moreover, shellac-PNIPAM nanoparticles adsorb specifically prothrombin at 37 °C (T > volume phase transition temperature, VPTT).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
