Abstract

Antimicrobial-modified cellulose fiber was prepared by covalently bonding β-cyclodextrin (β-CD) with cellulose fiber via citric acid (CA) and including ciprofloxacin hydrochloride (CipHCl) as antibiotics. Fourier transform infrared (FTIR) confirmed the esterification reaction between β-cyclodextrin citrate (CA-β-CD) and cellulose. Ungrafted cellulose fibers showed a little affinity to CipHCl, whereas β-CD grafted fibers increased the loading amount dramatically because the equilibrium amount was more than tripled to that of ungrafted ones. Meanwhile, the release process of CipHCl from β-CD grafted fibers was prolonged to reaches the equilibrium. The β-CD grafted fibers loaded with CipHCl showed excellent antibacterial activity against Escherichia coli and Staphylococcus aureus, the inhibition efficiency against E. coli was higher than that against S. aureu at the same fiber content generally.

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