Abstract
Preliminary Assessment of Glycemic Control and Body Fat Reduction Effects of Terminalia chebula Retz. Extract on Pre-diabetic Subjects
Highlights
Non-communicable diseases (NCDs) remain one of the leading causes of death worldwide that killed approximately 40 million people each year.[1]
The efficacy of T. chebula fruit water extract (TFWE) and placebo were compared in terms of reducing fasting blood sugar (FBS) levels, body mass indexes (BMI), body circumferences and skinfold thicknesses
The High‐pressure liquid chromatography (HPLC) analysis showed that gallic acid was a major phenolic compound with 33.23±0.857 mg/ g of TFWE, followed by chebulinic acid, chebulagic acid and ellagic acid as 13.12±0.303, 10.43±0.080 and 3.60±0.096 mg/g of TFWE, respectively
Summary
Non-communicable diseases (NCDs) remain one of the leading causes of death worldwide that killed approximately 40 million people each year.[1]. (Combretaceae) or black myrobalan is one of the most revered medicinal plants in Ayurvedic medicine and folk remedies worldwide. It is called the “king of medicines” due to its use in the prevention and treatment of many kinds of diseases.[5]. Objectives: The present study was a double-blind, placebo-controlled trial designed to study the effect of T. chebula fruit water extract (TFWE) in pre-diabetic subjects. The efficacy of TFWE and placebo were compared in terms of reducing fasting blood sugar (FBS) levels, body mass indexes (BMI), body circumferences and skinfold thicknesses. Conclusion: The administration of 2,000 mg TFWE per day was considered safe for the pre-diabetic healthy subjects with benefits in obesity management.
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