Abstract

SESSION TITLE: Pulmonary Rehabilitation SESSION TYPE: Original Investigation Slide PRESENTED ON: Monday, October 30, 2017 at 07:30 AM - 08:30 AM PURPOSE: Pulmonary rehabilitation (PR) improves quality of life (QoL) in patients with COPD in the short-term. However, its determinants of QoL following PR in the long-term are not well understood. We examined predictors of QoL of COPD patients who completed an 8-week PR in 2 years follow-up. METHODS: We conducted an eight-week PR program in a community-based setting. The PR comprised of 1 hour strength and aerobic exercises and 1 hour educational program. Patients completed the following outcome measures at baseline, eight and 104 weeks: dyspnoea measured by Medical Research Council (nMRC), quality of life measured by St-Georges Respiratory Questionnaire (SGRQ), exercise capacity by Incremental shuttle walk test (ISWT), depression by depression, anxiety and stress scale and anxiety (DASS) and anxiety assessed by anxiety inventory for respiratory disease (AIR). RESULTS: 165 COPD patients who completed the eight weeks PR followed for two years. Multivariate regression analysis of predictors of better QoL were satisfaction with the service, low dyspnoea, anxiety and depression scores and higher exercise capacity contributed to adjusted R-squared of 55% of the variance. Of these, 1% of the variance was predicted by satisfaction of service, 2% by anxiety using AIR, 5% by dyspnoea using nMRC, 14% by exercise capacity and 17% by depression DASS, respectively. Gender, age, smoking status and severity of lung function impairment were not associated with QoL. CONCLUSIONS: The clinical variables that predicted better quality of life were low anxiety, dyspnoea, depression score and higher exercise capacity. Physiological and behavioural factors were not related to QoL. CLINICAL IMPLICATIONS: Encouraging patients to engage in self-management and maintenance exercise programme following PR is worthy of consideration. DISCLOSURE: The following authors have nothing to disclose: Abebaw Yohannes, Sheila Dryden, Nicola Hanania No Product/Research Disclosure Information

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