Abstract

BackgroundPoor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes. This study sought to investigate the level of medication adherence to antidiabetic therapy and to identify possible predictors of poor adherence.MethodsA hospital based cross-sectional study was conducted from July 2018 to June 2019 among randomly selected follow-up T2D patients at a hospital diabetes clinic. Data were collected through patient interviews, followed by medical chart review. Adherence to antidiabetic therapy that we assessed patients’ responses using validated Brief Medication Questionnaire (BMQ). To identify predictors of poor medication adherence, binary logistic regression analyses were performed using SPSS version 25. Statistical significance was set at p value ≤ 0.05.ResultsOf the total 357 study participants, 25% were non-adherent to their antidiabetic therapy. Predictors statistically associated with poor adherence were; being female gender (AOR = 1.71, 95% CI 1.01–2.76), and presence of at least one diabetic complication (AOR = 2.02, 95% CI 1.02–3.22). Participants with having at least primary level of education were more likely to adhere to anti-diabetes medication (AOR = 0.42, 95% CI 0.18–0.96). The most common self-reported reasons for non-adherence were forgetfulness, unavailability of medication plus the unaffordability of anti-diabetes medications.ConclusionsThe proportion of participants’ adherent to anti-diabetes therapies was suboptimal. Being female, the presence of chronic diabetic complications and having no formal education were the main predictors of poor adherence. Strategies that aimed at improving adherence to antidiabetic medications deemed to be compulsory.

Highlights

  • Poor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes

  • The mean (± standard deviation (SD)) age of the study participants was 59.4 ± 13.1 years and more than half, 188 (52.7%) of them were in their middle age (41– 60) years

  • Two-fifth (39.5%) of the participants had at least College and above level of education (Table 1)

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Summary

Introduction

Poor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes. Non-adherence to the medical regimen is a major clinical problem in the management of patients with diabetes is a global problem. Demoz et al Diabetol Metab Syndr (2020) 12:62 the recommended therapies While, this situation is far worse than in the developing world [3]. Nonadherence to medication is common in patients with diabetes [5] and non-adherence compromises safety and treatment effectiveness, leading to increased morbidity and mortality rates. This contributes to significant direct and indirect costs in the healthcare system [6,7,8]

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